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DNA replication is a complex, fast, and precise process involving enzymes like topoisomerase, helicase, and polymerase. In E. coli, polymerase can replicate up to 700+ base pairs per second. Initially, one mistake occurs for every 10 million nucleotides, but proofreading reduces errors to one in a billion.
That is, how does a cell know when and how to migrate, divide, or differentiate? Broadly speaking, there are two kinds of information that guide cells' behavior: Intrinsic (lineage) information is inherited from the mother cell, via cell division.
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Antiparallel structure of DNA strands (video) | Khan Academy
khanacademy.org DownloadRestriction enzymes & DNA ligase - Khan Academy
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