Hvorfor har ikke alle pasienter god effekt av Paralgin forte ...

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I Paralgin forte er virkestoffene kodein og paracetamol. Omdannelsen fra kodein til morfin er viktig, siden kodein er et inaktivt pro-drug uten noen smertestillende effekt. Utfordringen ved bruk av kodein, er at ulike pasienter vil danne svært ulik mengde morfin, og den smertestillende effekten er derfor uforutsigbart.


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