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Ani 9 is a potent and selective TMEM16A (Anoctamin-1; ANO1) blocker (IC 50 = 77 nM). Displays no effect on ANO2 activity (at 10 μ M). Also exhibits no effect on intracellular calcium signaling or CFTR and ENaC channel activity (at 30 μ M). The technical data provided above is for guidance only.
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