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Introduction Mitosis is the phase of the cell cycle when newly replicated chromosomes assemble on the mitotic spindle for distribution to the daughter cells. The mitotic spindle is principally composed of microtubules, which assemble from α/β tubulin heterodimers. α/β tubulin dimers are guanine nucleotide-binding proteins that associate in a head-to-tail orientation to produce a polarized ...
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