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KEY POINTS Aztreonam (Azactam) is a monobactam that binds to penicillin binding proteins (PBP) and interferes with cell wall synthesis for sensitive bacteria Has a high affinity for PBP-3 Has an inhaled formulation (brand name Cayston) Has activity against Gram negative bacteria ONLY, like Pseudomonas aeruginosa Beware bacterial resistance to ...
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