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9am cortisol between 100 and 350nmol/L may be normal, and cannot be used to exclude or diagnose adrenal insufficiency. 9am cortisol <50 nmol/L after overnight dexamethasone suppression exclude endogenous Cushing's syndrome. A random (non-9am) cortisol or a value when the patient is taking steroid treatment is uninterpretable.
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