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Usual Adult Dose for Pain. Initial dose: Acetaminophen (300 to 600 mg) and codeine (15 to 60 mg) orally every 4 hours as needed for pain. Titrate to a dose that provides adequate analgesia and minimizes adverse reactions; Maximum doses: Acetaminophen 4000 mg/24 hours; Codeine: 360 mg/24 hours Comments:
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