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Methods: This phase 1 study (NCT05424380) will evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and cytotoxicity of GSK3745417 administered as an intravenous infusion. Eligible patients will be 18 to 75 years of age with a diagnosis of relapsed or refractory AML (World Health Organization criteria) or high-/very high-risk MDS by (Revised International ...
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