为什么可以通过检测孕妇的血液来检测胎儿的 DNA？ - 知乎
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而游离胎儿dna与母体混合存在，难于分离游离胎儿dna，含量少、片段短等特点使得利用常规 pcr 技术只能分析是否存在游离胎儿dna，如进一步获得胎儿基因组信息还需一种高通量测序平台。利用游离dna高通量测序可对每次产生的上百万的胎儿和孕妇dna分子进行检测。
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