什么是生长分化因子15(GDF-15)？ - 知乎
20 June 2025 admin
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gdf-15主要通过以下机制发挥作用：干扰dc的激活和成熟；减少树突状细胞对t细胞的诱导和激活作用；阻断有效的免疫细胞外渗和肿瘤浸润；抑制t细胞和nk细胞对肿瘤细胞的杀伤作用；通过产生和增强调节性t细胞的功能，在肿瘤组织中诱发免疫抑制。
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