Phage Paride can kill dormant, antibiotic-tolerant cells of Pseudomonas ...

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a newly isolated Pseudomonas aeruginosa phage, named Paride, can directly replicate and induce the lysis of deep-dormant hosts. While non-growing bacteria are notoriously tolerant to antibiotic drugs, the combination with Paride enables the carbapenem meropenem to eradicate deep-dormant cul-tures in vitro and to reduce a resilient bacterial infection of a tissue cage implant in mice. Our work ...


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