Tabular SmPC - Lundbeck
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The exposure to vortioxetine increased 2,3-fold for AUC when BRINTELLIX 10 mg/day was co-administered with bupropion (a strong CYP2D6 inhibitor) 150 mg twice daily for 14 days in 44 healthy subjects. The co-administration resulted in a higher incidence of adverse reactions when
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