疫苗前沿|柯萨奇B组病毒:引起心肌炎与1型糖尿病的潜在 ...

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CVB1:主要与1型糖尿病 (T1D)有关,也可导致特征性胸肋痛、无菌性脑膜炎和新生儿败血症; CVB2:常可以从急性心肌炎、无菌性脑膜炎和急性脑膜炎患者中分离出,可导致多器官衰竭和心源性休克; CVB3:其感染与心肌炎有关,常导致扩张型心肌病 (DCM)和心力衰竭; CVB4:与T1D的发生有关; CVB5:与手足口病、无菌性脑膜炎、病毒性脑炎、急性迟缓性麻痹、心肌炎和T1D等疾病有关; CVB6:相关的感染报告数量不多,但有报告称,合并感染CVB6与CVB5的患者常有急性发热病、皮疹、严重急性呼吸道疾病、脑膜炎、心肌炎和/或心包炎症状。


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