为什么质粒导入受体细胞不会被免疫攻击而DNA会? - 知乎
14 July 2025 admin
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质粒会啊，PNAS上有一篇文章研究了这个问题， 质粒 会激活细胞内cGAS产生cGAMP,通过STING激活 免疫通路。之所以你有这种错觉，可能是因为我们常转染质粒的细胞是293T,但这种细胞系是cGAS STING均缺失的。
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