somatic和germline突变有什么区别,问什么在研究癌症的过程中要区分这两种突变? - 知乎

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Somatic mutations主要是由于「体细胞(somatic cells)突变」导致,皮肤,肝脏,骨髓,眼睛等的细胞均为体细胞,但不包含生殖细胞。 遗传性 Germline mutations 本质上是遗传性的,因为它们发生在参与受精的配子( gametes)中。


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